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Factor xiii normal range

The zymogen plasma FXIII (pFXIII) circulates in plasma as a tetramer (FXIII‐A 2 B 2) consisting of two catalytic A subunits (FXIII‐A) and two carrier/protective B subunits (FXIII‐B). Conclusions: The survey determined the normal range of factor XII activities in healthy Chinese and identified mutations as well as a biased representation of a polymorphic nucleotide in subjects with abnormally low activities. The results provide an essential basis for the diagnosis of FXII deficiencies in Chinese. 2020-09-30 · Factor XII, also known as Hageman factor, is indicated when factor XII deficiency is suspected. The reference range of factor XII is 60-150% of normal.

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16. Description Normal Reference (Factor Assay Control) Plasma. The VisuCon-F Frozen Normal Plasma is a Normal Reference (Factor Assay Control) Plasma for use in the quality control of quantitative coagulation assays, including Prothrombin Time (PT), Activated partial thromboplastin time (APTT) and fibrinogen, in the normal range.

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were within normal range except for FXIII.

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Symptoms can become apparent at any age. Individuals of any race or ethnicity can be affected. The incidence of factor XIII deficiency has been estimated to be between 1 in 2,000,000-5,000,000 people in the general population. Coagulation factor XIII is a protransglutaminase that has a major role in the final stage of blood coagulation .

Preferred first-line test to diagnose inherited or acquired factor XIII (FXIII) deficiency. Appropriate for evaluation of patients with a bleeding disorder who present with normal prothrombin time (PT), activated partial thromboplastin time (aPTT), and platelet count test results.
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